Fabian Ackle

Biochemistry, protein engineering and structural biology

Portrait photo of Fabian in the lab

About me

I am a PhD student in the Seeger Lab at the University of Zurich. My research focuses on protein trafficking in the early secretory pathway. I am developing and applying methods for studying cargo receptors using high-throughput mutational scanning. Additionally, my research interests include single-domain antibodies (nanobodies) and their application in structural biology.

square academic cap icon Google Scholar square academic cap icon GitHub ORCID iD icon https://orcid.org/0000-0002-7199-5004

Contact

Follow me on Twitter @f_ackle or write me an email fackle@imm.uzh.ch.

Publications

Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1

L Loeff, A Kroupova, I Asanovic, FM Boneberg, MM Pfleiderer, A Ferdigg, F Ackle, J Martinez, M Jinek - bioRxiv, 2023
DOI: 10.1101/2023.04.06.535761

Molecular architecture of the human tRNA ligase complex

A Kroupova, F Ackle, I Asanović, S Weitzer, FM Boneberg, M Faini, A Leitner, A Chui, R Aebersold, J Martinez, M Jinek - Elife, 2021
DOI: 10.7554/eLife.71656